Absolutely nothing to do with PD comics, but I thought my idea was rather clever, and the execution rocks:
http://www.comicartfans.com/GalleryPiece.asp?Piece=938012&GSub=108696From the artist, Michael Walsh:
"1. Layout the page digitally at a small size.
2. Blow up digitally and pencil in photoshop with a tablet.
3. Print out in a light non-photo blue onto bristol paper.
4. Usually I jump right in with ink onto the bristol but sometimes I'll do a bit of traditional pencilling if I want to work something out a bit more."